Will you be arriving by bicycle?
It takes about ten minutes to get to the museum by bicycle from Amsterdam Central Station. You can park your bicycle along the canal.
By public transport?
From Amsterdam Central Station you can take:
Bus 285 or 287 to the Rembrandtplein bus stop
Tram 4 or 14 to the Rembrandtplein tram stop
Tram 24 to the Muntplein tram stop
Metro routes 51, 53 or 54 to the Waterlooplein metro station
Metro route 52 to the Vijzelgracht metro station
The easiest way to get to the museum by car is from Stadhouderskade (s100) and then take Westeinde-Frederikspark and Utrechtsestraat. Parking spaces are available at the Stadhuis-Muziektheater parking facility. There are also parking meters for parking in the vicinity of Herengracht itself, but you should also know that it is often difficult to find a spot.
Then get off at the Stadhuis-Muziektheater stop at Waterlooplein, or at a stop on Herengracht.